Algumas partes do texto estão em português / Some small parts are in Portuguese language 

Major contributions by Doctor Mesquita to the Medical Science

• 1º case of ventricular aneurysmectomy performed by Charles P. Bailey (1954) (Heart Aneurysm Surgery)
• 1º case of right ventricular infarction with diagnosis realized in vivo inside new electrocardiographic patterns contradicting the cavity theory and confirming the vectorial theory (1958). (The Vectorial Theory)
• 1º case of unstable angina pectoris ceased as a immediate result of cardiotonic administration; Myogenic Theory confirmation (1972). (The Myogenic Theory)

Some Personal Communications to Dr. Mesquita referring to Myogenic Theory of Myocardial Infarction, to Heart Aneurysm Surgery by Bailey and about the first right ventricular infarction diagnosis:

Ary L. Goldberger - USA (1), Robert Roberts - USA (2), Frank I. Marcus - USA (3), M. S. Pathy - England (4), Bernard Lown - USA (5), Isabel Coma-Canella - Spain (6), J. Candell Riera - Spain (7), Myron Prinzmetal (8) - USA, Charles P. Bailey – USA (9)  

Small history of the Myogenic Theory

Doctor Mesquita, who started clinical activities in 1941, very early (in 1954) experienced great frustration with the failure of anticoagulants as logical preventives for the myocardial infarction. Anticoagulants were abandoned worldwide after 1969, shaking down the classic thrombogenic theory as origin of the myocardial infarction.

In 1972, Doctor Mesquita developed the Myogenic Theory, in a pathophysiological basis where the origin of myocardial infarction is myogenic and not thrombogenic, as opposed to the stated by the classical theories. He started from that time to treat patients with cardiotonic drugs based on his myogenic theory, in a large success not equaled by the traditional treatment. Due to his concepts and results, Doctor Mesquita awarded in 1975 the "Ernst Edens - Traditionspreis", by the "Internationale Gesellschaft Für Infarktbekampfung" (International Society Against Myocardial Infarct), located in Stuttgart - Germany (1), and a special report by Bunte Magazine, Germany in 10/04/1980 (2).

• 1948: Developed a new classification of “Incomplete Bundle Branch Block with the discovery of 2 new types of IBBB”. Republished on the Brazilian Cardiology Society website in  2002 at http://www.cardiol.br/tunel/ago/new/015.pdf ). Additional information at http://www.infarctcombat.org/arrhythmias-02.html
• 1999:  Presented at the I Virtual Congress of Cardiology a paper that confirms the Prinzmetal's Theory of Accelerated Conduction”. It was entitled “Exceptional Patterns of the Wolff-Parkinson-White Syndrome in Rhythm and AV Nodal Tachycardia” published at http://pcvc.sminter.com.ar/cvirtual/tlibres/tnn2346i/tnn2346i.htm

Published many other papers about Wolff-Parkinson-White Syndrome, including in partnership with Myron Prinzmetal and Maurice Lev in 1961, at http://circ.ahajournals.org/cgi/content/abstract/24/1/41

Papers published in English at Internet:

1. Myogenic Theory of Myocardial Infarction - Book ( download free of charge - Summary in English)

2. Interview about the Myogenic Theory to Infarct Combat Project, 1999

3. Myogenic Theory Explains

4. Decalog for CHD Patients

5. Angina as Red Flag for CHD Patients

6. Myogenic Theory, CHD Cardiotonic Therapeutics, ECG diagnosis of Right Ventricular Infarction, etc.

7. Tribute to Doctor James Bryan Herrick

8. Myocardial Infarction diagnosis by ECG (Library)

9. There are no Justifiable Reasons to Realize Costly and Aggressive Management for Acute Coronary Syndromes

10. Reinvigorating old ECG concepts: "Nodal AV Rhythm - maintenance of 3 morphological types"  

11. Reinvigorating old ECG concepts: "Incomplete Bundle Branch Block: distinction of types 1a and type 2 from our classification (1948)".

12. Reinvigorating old ECG concepts: "Sino-Atrioventricular Symbiotic Rhythm (SA-AV) "

13. Batista Partial Ventriculectomy Procedure

• (Books, Titles and Bibliography at the end of the page)

Algumas homenagens póstumas

• Tributo ao Doutor Quintiliano H. de Mesquita (1918 - 2000), publicado nos Arquivos Brasileiros de Cardiologia, Janeiro de 2001. "Após o falecimento, o tardio mas justo reconhecimento"

• Homenageado pela Sociedade Paraibana de Cardiologia e SBC/PB que atribuíram ao melhor trabalho classificado nas apresentações de temas livres do IV Congresso Paraibano de Cardiologia o prêmio “Quintiliano Mesquita” – também no mesmo informativo da Sociedade Paraibana de Cardiologia de Maio de 2001 a publicação do artigo “Exemplo de Vida”, pelo Dr. Paulo Bezerra de Araújo Galvão.

• Homenagem do Dr. Cláudio A S Baptista, através do artigo “Quintiliano de Mesquita: Um Princípio, Uma Luta” publicado no Jornal da  Sociedade Brasileira de Cardiologia de Nov/Dez de 2000 e republicado em História da Cardiologia pela SBC, em seu site na Internet.

• Quintiliano H. de Mesquita: O Depoimento de um aliado e colaborador, por Carlos Monteiro, 2003. (Depoimento)

• Quintiliano H de Mesquita: A História e a Luta de um Gênio da Medicina do Século XX, por Carlos Monteiro, 2003 (A história e a luta).

Prêmio Recebido e Importantes Homenagens em vida

• Da Concessão do Prêmio Ernst Edens em 1975 pela Sociedade Internacional de Combate ao Enfarte

• Reportagem Revista Bunte de 10.04.1980, Offenburg – Alemanha “È Assim que um Brasileiro Combate o Enfarte do Coração” (So Bekämpft ein Brasilianer Den Herzinfarkt)

• Da Saudação ao Quintiliano H. de Mesquita por Miranda Freire* Durante o I Encontro de Cardiologia da Paraíba (15 – 19 de julho de 1975)

A relação das contribuições realizadas pelo Doutor Mesquita para a Ciência Médica

- Artigo "Gloriosa Trajetória e Rica Memória do Instituto de Cardiologia do Hospital Matarazzo "1945-1979" apresentando 33 Trabalhos Inéditos na Literatura Mundial e 41 Trabalhos Inéditos na Literatura Nacional (1942 a 2000).

Livro e Lista Parcial de Artigos publicados em Português na Internet:

• Livro Teoria Miogênica do Enfarte Miocárdico (Download Gratuito!)

• Entrevista sobre a Teoria Miogênica concedida ao Infarct Combat Project, 1999.

• A Teoria Miogênica Explica ou "A Teoria Trombogênica Desabou e a Ortodoxia Não Notou"

• Memórias sobre Nosso Abandono da Terapêutica Anticoagulante em 1954

• Memórias sobre nossa contribuição para a cirurgia de aneurisma do coração (Aneurismectomia ventricular) praticada por Bailey em 1954

• Memórias sobre nossa contribuição para o estudo dos bloqueios de ramo

• Memórias sobre nossa contribuição para o estudo da síndrome de Wolff-Parkinson-White

• Memórias sobre nossa contribuição para o estudo do enfarte do ventrículo direito

• O Decálogo do Coronário

• Excepcionais Registros da Síndrome de Wolff-Parkinson-White no Ritmo e na Taquicardia Nodal AV Confirmando a Teoria da Condução Acelerada de Prinzmetal (Apresentado no I Congresso Virtual de Cardiologia em 1999 e publicado em maio de 2002 na revista Ars Cvrandi)

• Na Prevenção e Tratamento da Angina Instável e Enfarte Miocardico Drogas Eficazes Superam o Intervencionismo Compulsivo

• Na Doença Coronário-Miocardica a Insuficiência Cardíaca É Mais Freqüente que o Enfarte Miocardico e o Cardiotônico é a Solução

• Enfarte do Miocárdio: Prevenção e Tratamento por Cardiotônicos x Angioplastia e/ou Cirurgia de Ponte de Safena (Estatísticas)

• Aspectos Clínicos e Coronário-Miocárdicos Compatíveis Com a Teoria Miogênica e Conflitantes Com a Teoria Trombogênica do Enfarte Agudo do Miocardio

• Médico Brasileiro Cria Cirurgia que Deve Evitar o Transplante Cardíaco

• Digital na Clínica Diária: Comodidade, Eficácia e Segurança

• Transplante Usa Células da Perna no Coração (e sua indicação ampliada dentro dos conceitos da Teoria Miogênica)

Sua participação em importantes momentos da formação da cardiologia brasileira na década de 40 (Fotos)

• Nos cursos intensivos de cardiologia do Hospital Municipal de São Paulo, sob a direção do Dr. Pazzanese

• No curso de eletrocardiografia dado pelo Dr. Frank Norman Wilson, em 1942

• Nos cursos de eletrocardiografia dados por ele no Instituto de Cardiologia do Hospital Matarazzo em São Paulo

Books:

• Arrhythmias - Imprensa Universitária, Universidade Federal da Paraíba, 1971
• Myogenic Theory of Myocardial Infarction - Gemini, 1979 - ( download free of charge - Summary in English)
•  Informative bulletin: Infarct - How to treat and avoid it only with drugs, edited by the author, 1983
• How to escape from coronary bypass surgery and myocardial infarct only with drugs - Icone, 1991
• Boycotted drug replaces coronary bypass surgery - Compset, 1996

Bibliography:

1. Heart aneurysm. Presentation of case operated by Bailey, Rev Hospital N.S. Aparecida, 1956:9:151 with reprint by Rev Hospital Matarazzo numbers 3 and 4 - Volume IX, 1956
2. Anticoagulant and myocardial infarction. Publicações Médicas, 1962; 33:3
3. Contribution to the study about right ventricular infarction. Arq. Bras Cardiol, 1960; 13:162
4. Electrocardiographic aspects of right ventricular infarction. Arq Bras Cardiol, 1963;16:113
5. Effects of strophanthin K, by intravenous route, in treatment of clinical infarctioning picture and of myocardial infarction. Revta. Bras. Clin. Terap, 1973;2:647
6. Use of cardiotonic in treatment of angina pectoris and impending myocardial infarction syndrome, Revta. Bras. Clin. Terap., 1973; 5:309
7. Cardiotonic in the prophylaxis of myocardial infarction. Revta. Bras. Clin. Terap, 1976; 5:309
8. Functional preservation of ischemic myocardium by long time on use of cardiotonic. Medicina de Hoje, 1978; 154
9. Cardiotonic and acute myocardial infarction in man. Revta. Bras. Clin. Terap, 1981; 10:645
10. "QS" wave in right ventricular infarction: cavity theory and vectorial theory - Report of 2 cases, Arq. Bras. Cardiol, 1981; 36/2:125
11. The cardiotonic in chronic coronary disease and prevention of myocardial infarction Rev. Bras. Med, 1982; 39:359; Rev. Bras. Clin. Terap, 1982; 11:794
12. First myocardial infarction in silent chronic coronariopathy: angiographic coronary and ventriculographic aspects. Rev. Bras. Med. 1982; 39:427
13. The cardiotonic in intermediate coronary syndrome. Rev. Bras. Med. (Cardiologia), 1983; 2:317
14. A new and simplified electrocardiographic classification of acute myocardial infarction. Rev. Bras. Med. (Cardiologia), 1985; 4:34
15. Importance of age as a prognostic factor in acute myocardial infarction. Rev. Bras. Med. (Cardiologia) , 1985; 4:34
16. Association of proscilaridine-A and verapamil by oral route in treatment of unstable angina pectoris. Rev. Bras. Med. (Cardiologia), 1985; 4:99
17. Pathophysiological and therapeutics implications of acute myocardial infarction in view of coronary arteries either angiographically normal or with pervious stenotic lesions. Rev. Bras. Med. (Cardiologia), 1985; 4:187
18. Point of view. Why Myogenic Theory and Not Thrombogenic Theory. Arq. Bras. Cardiol. 1994;62 (4):271, Republished at Internet in 2003.
19. Electrocardiogram of right ventricular infarction. Historical and critical evolution. Ars Cvrandi, 1995;28:12-49
20. Unstable Angina: Atherosclerotic Etiology, Myogenic Pathophysiology and Cardiotonic Therapeutic. Ars Cvrandi, 1999;32: Monothematic in Cardiology (Part III)
21. Cardiotonic: Insuperable in preservation of myocardial stability as preventive of acute coronary syndromes and responsible for the prolonged survival. Study of almost 1200 cases - 28 years of follow-up, Ars Cvrandi, May 2002;35:3
22. Effects of cardiotonic + coronary dilator in stable coronary myocardiopathy, with or without previous infarction in the long run. Ars Cvrandi, September 2002;35:7

Titles:

1. Honorary Professor of Medicine from the Federal University of Paraíba state.
2. Founder and Chief of the Angiocardiology Institute of Matarazzo Hospital, 1945-1979.
3. Founder Membership of the Brazilian Society of Cardiology.
4. Founder Membership of the Brazilian Society of Angiology.
5. Distinguished Member of the Cardiology Society from Paraíba state.
6. Founder and Emeritus Member of the Academy of Medicine from Paraíba state.
7. Executive Director of Instituto de Combate ao Enfarte do Miocárdio 1999/2000 - São Paulo, Brazil.
8. Founder and member from the board of Infarct Combat Project 1999/2000

Instituto de Combate ao Enfarte do Miocárdio

Website: http://www.infarctcombat.org/OInstituto/home.html

Email: instituto(at)infarctcombat.org

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